Discontinuation and nonpublication of lumbar spinal fusion clinical trials
A 24-year registry-based analysis of Phase 3 and 4 randomized controlled trials registered on ClinicalTrials.gov.
The question
How often do spine fusion trials stop early or never publish, and what does that cost the patients who enrolled?
Why it matters
Surgeons choose fusion techniques from trial evidence. Results that go missing leave gaps in that evidence.